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doi: 10.3389/fvets.2021.621732 Received 26 October 2020 Accepted 25 January 2021 Published 18 February 2021 Volume 8 - 2021 Edited by Nora Mestorino, National University of La Plata, Argentina Reviewed by Pieter Annaert, KU Leuven, Belgium

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One of the better characterized metabolic phenotypes present in tumor cells is the Warburg effect, which gives preference to ATP generation through glycolysis, even under normal oxygen concentrations, over ATP synthesis through the electron transport chain in the mitochondria (Warburg, 1956